(Coordinator: ASSOC. PROF. Beata Sikorska)
Neurodegenerations are chronic, progressive, debilitating diseases that are increasing in prevalence in Europe. Their treatment is, at the very best, only symptomatic, since no specific curative therapies are available. As a result, they present an increasing burden of utmost social impact in aging European societies.
The major focus of this group will be newfound knowledge on the etiology and pathogenesis of neurodegeneration particularly the role of toxic proteins, the formation of pathogenic deposits both inside and outside the cell, and the role of neuroinflammation and neuronal stem cells. Furthermore, we will search for novel mutations and polymorphism of putative pathogenetic significance. This research will contribute to an expanded classification of neurodegenerative disorders for both clinicians and diagnostic neuropathologists, allowing the identification and selection of new targets for therapeutic intervention.
The following foreign institutions will be partnering with Research Area II :
- Institute of Neurology Medical University of Vienna – prof. Johannes Hainfellner
- Institute of Neurology Medical University of Vienna – dr Gabor Kovacs
- John A Burns School of Medicine University of Hawaii – prof. Richard Yanagihara
- GCD Surveillance Unit, Edinburgh, UK – prof. James Ironside
- Clinical Institute of Neuropathology, Medical University, Vienna – prof. Herbert Budka