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Pathogenesis and prevention of respiratory, kidney and and cardiovascular diseases of the old age
August 27, 2013

(Coordinator: Assoc. Prof. Wojciech Piotrowski)

Chronic respiratory , kidney and cardiovascular disorders are among the most common comorbidities in the elderly. Asthma and Chronic Obstructive Pulmonary Dissease (COPD) are progressive inflammatory diseases of the airways, and their course may be complicated by various co-morbidities (i.e. ischaemic heart disease, heart insufficiency, diabetes, osteoporosis, lung cancer, depression and cognitive disorders).

Current tools used for prevention of excerbations and for routine monitoring of these diseases focus mainly on the parameters describing functional status of the respiratory system, and do not cover other aspects of these complex diseases. Therefore, there is a need for new approaches including continuous monitoring of patients’ well-being and airway function and further assessment of immunological status ( including increased susceptibility to infections). Furthermore, COPD, coronary artery disease and chronic heart failure occur commonly and are associated with similar systemic inflammatory reactions. One of important factors leading to development of cardiovascular disease, particularly in elderly patients, is a nondiagnosed and untreated renal disease.

The following foreign institutions will be partnering within Research Area III

  1. Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College, London, UK Leader: Professor Sebastian L. Johnston,
  2. University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham. Leader: Prof. Gregory Y.H. Lip
  3. Department of Cardiology, Oslo University Hospital, Ullevaal, Oslo. Leader: Prof. Sverre E. Kjeldsen
  4. Department of Clinical Biochemistry, Royal Free Campus, University College London Medical School, University College London. Leader: Prof. Dimitri P. Mikhailidis
  5. Centre for Allergy Research, Karolinska Institute. Leader: Prof. Sven – Erik Dahlen
  6. Immunology Research Institute, Davos, Switzerland. Leader: Prof. Cezmi Akdis

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